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ESR2-regulated genes in gonadotropin-stimulated rat oocytes

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NIAID Data Ecosystem2026-04-25 收录
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ESR2 mutant female rats are infertile. Oocyte maturation is defective in ESR2 mutants and they fail to ovulate . We are investigating the role of estrogen-signaling via ESR2 during gonadotropin-induced oocyte maturation. Oocytes were isolated from the ovaries of four-week-old wild type and ESR2 mutant female rats injected with PMSG and hCG. Total RNA was isolated from the oocytes and the whole oocyte transcriptome was detected by RNA-sequencing.

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2019-09-13
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