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Detectie van tumorweefsel met behulp van Bevacizumab-IRDye800CW in combinatie met een optisch beeldvormingssysteem bij patiënten die de HIPEC procedure ondergaan, een haalbaarheidsstudie.

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https://www.omicsdi.org/dataset/ecrin-mdr-crc/18903
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Interventions: Patients scheduled for a HIPEC procedure for peritoneal carcinomatosis of colorectal origin will be consented for this study. There will be three study related visits. During a screening visit (visit 1), eligibility will be evaluated and patient characteristics will be collected. During the second visit 4.5 mg of bevacizumab-­‐IRDye800CW will be administered intravenously. The patient will then be observed for 1 hour post administration. One day after administration of the tracer (visit 3 one day before surgery) the patient is administered to the hospital as in the standard procedure, or the patient can stay after the tracer injection if this more convenient for the patient. During the HIPEC procedure the fluorescent imaging will be performed and data acquired. Primary outcome(s): Visualization of fluorescent tumor tissue confirmed by ex vivo immunohistochemistry or fluorescence microscopy of excised specimen. Study Design: N/A: single arm study, Open (masking not used), N/A , unknown, Other
创建时间:
2014-07-15
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