Crystal structure of integrin avb6 headpiece in complex with compound MORF-627
收藏Protein Data Bank Japan2024-11-27 更新2026-04-19 收录
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Crystal structure of integrin avb6 headpiece in complex with compound MORF-627 Descriptor: (2S)-{5-fluoro-2-[(6S)-5-oxaspiro[2.5]octan-6-yl]phenyl}{(3R)-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy]pyrrolidin-1-yl}acetic acid, 17E6 Fab heavy chain, 17E6 Fab light chain, ... Authors: Monroy, M.F, Qiao, Q, Lin, F.Y. Deposit date: 2024-08-05 Release date: 2024-11-13 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.53 Å) Cite: The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin alpha v beta 6 Inhibitor for Fibrosis. J.Med.Chem., 67, 2024
创建时间：
2024-08-05
