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Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with IACS-70099

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of the indoleamine 2,3-dioxygenagse 1 (IDO1) complexed with IACS-70099 Descriptor: (2R)-N-(4-chlorophenyl)-2-[(1R,3S,5S,6r)-3-(5,6-difluoro-1H-benzimidazol-1-yl)bicyclo[3.1.0]hexan-6-yl]propanamide, Indoleamine 2,3-dioxygenase 1 Authors: Leonard, P.G, Cross, J.B. Deposit date: 2021-03-25 Release date: 2021-09-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme. J.Med.Chem., 64, 2021
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2021-03-25
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