Transcriptomic profiling of ovarian cancer tissue

Epithelial ovarian cancer (EOC) has the highest mortality among gynecological carcinomas. The lack of specific markers for prognostic determination of EOC progression hinders the search for novel effective therapies.The aim of the present study was to explore differences in whole transcriptome profile in ovarian cancer patients with defined platinum resistance status (platinum-sensitive or platinum-resistant), which was based on platinum-free interval with effort to find potential players in drug resistance development.