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Hyperactive RAS/MAPK introduces cancer-specific mitotic vulnerabilities. Hyperactive RAS/MAPK introduces cancer-specific mitotic vulnerabilities

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA723590
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资源简介:
We performed tanscriptional profiling of ARPE19 and four isogenic transformed cells lines in which Ras or two downstream pathways, MAPK or PI3K/mTOR, were up-regulated. The purpose of this study is to understand how Ras signaling impacts kinetochore function. Overall design: mRNA-seq transcriptome profilng performed in triplicate on each of the five cell lines.
创建时间:
2021-04-21
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