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Effect of Gut Microbiota on Neurodevelopment Disorder-Associated Behavioral Abnormalities in CLC4 Knockout Mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP576775
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Neurodevelopmental disorders (NDDs) are characterized by deficits in the nervous system, with chloride ion channel 4 (CLC4) playing a crucial role. Increasing evidence suggests an association between the gut microbiota and NDD; however, the underlying mechanisms remain unclear. This study examined whether CLCN4 knockout (KO) alters the gut microbiota composition and contributes to NDD-like behaviors in mice.
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2025-04-16
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