Stepwise Ligand Exchange for the Preparation of a Family of Mesoporous MOFs

A stepwise
ligand exchange strategy is utilized to prepare a series
of isoreticular bio-MOF-100 analogues. Specifically, in situ ligand exchange with progressively longer dicarboxylate
linkers is performed on single crystalline starting materials to synthesize
products with progressively larger mesoporous cavities. The new members
of this series of materials, bio-MOFs 101–103, each exhibit permanent mesoporosity and pore sizes ranging
from ∼2.1–2.9 nm and surface areas ranging from 2704
to 4410 m2/g. The pore volume for bio-MOF 101 is 2.83 cc/g. Bio-MOF-102 and 103 have
pore volumes of 4.36 and 4.13 cc/g, respectively. Collectively, these
data establish this unique family of MOFs as one of the most porous
reported to date.