Coefficients for final gene expression models

Coefficients for elastic net models fit using various -omics data types on the TCGA dataset, for the 217 target genes in the "all data types" analysis. <br> Columns correspond to target genes (gene symbols), and rows correspond either to principal components (for 27K and 450K methylation), -omics features (all other data types), or covariates (cancer type indicator variables or log(mutation burden)). <br> An 'NA' value in a cell indicates that feature was not used in the model for the corresponding gene (for a gene feature this means that gene was not in the top 8000 genes by MAD, for a cancer type feature this means that cancer type was not included in the training set based on our mutation filters). A 0 value in a cell indicates that feature was included in model training, but it was not selected by the elastic net feature selection algorithm. <br> Hyperparameter selection procedure is described in the methods section of the paper: https://greenelab.github.io/mpmp-manuscript/ <br> <br>