Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-169

NIAID Data Ecosystem2026-05-02 收录

寄生虫靶点结构

抗恰加斯病药物发现

数据链接：

https://www.rcsb.org/structure/3W2L 数据链接链接失效反馈

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资源简介：

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-169

创建时间：

2024-10-30

LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS

寄生虫靶点结构

抑制剂设计

LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS Descriptor: GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, N-1,2,3,4-TETRAHYDRONAPHTH-1-YL-2'-[3,5-DIMETHOXYBENZAMIDO

Protein Data Bank Japan2024-02-07 更新30

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

抗恰加斯病药物发现

多胺转运蛋白抑制

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport process

NIAID Data Ecosystem30

Crystal structure of Schistosoma mansoni HDAC8 complexed with J1038

寄生虫靶点结构

基于结构的药物设计

Crystal structure of Schistosoma mansoni HDAC8 complexed with J1038 Descriptor: (2R)-2-methyl-3-oxo-4H-1,4-benzothiazine-6-carbohydroxamic acid, HISTONE DEACETYLASE 8, POTASSIUM ION, ... Authors: Mare

Protein Data Bank Japan2023-12-20 更新20

Computational identification of chemical compounds with potential anti-Chagas activity using a classification tree

抗恰加斯病药物发现

计算机辅助药物筛选

Chagas disease is endemic to 21 Latin American countries and is a great public health problem in that region. Current chemotherapy remains unsatisfactory; consequently the need to search for new drugs

NIAID Data Ecosystem30

Adenosine kinase from Schistosoma mansoni in complex with 2-fluoroadenosine

寄生虫靶点结构

抑制剂复合物

Adenosine kinase from Schistosoma mansoni in complex with 2-fluoroadenosine

NIAID Data Ecosystem20