Effects of systemic injection of a selective dopamine D1-like receptor antagonist, SCH23390, on the number, duration, and relative power of HVSs, and the HVS-related coherence between the M1 and GP.

A: number of HVSs. B: duration of HVSs. C: representative averaged relative power spectral density curve of the M1 cortex (ECoG), and the GP LFP recorded from saline-treated rats (black lines) and SCH23390-treated rats (red or blue lines; the proportion in the 40–70 Hz range was omitted from the curve because of their near-to-zero values). D: relative power of both the M1 cortex and GP LFP in the frequency bands associated with HVS oscillations. E: averaged coherence curves of the M1–GP pair in the saline-treated rats (black lines) and SCH23390-treated rats (red or blue lines; the proportion in 40–70 Hz range was omitted from the curve for their near-to-zero values). F: coherence values relating to the HVSs. SAL, saline; SCH 1.0, SCH23390 1.0 mg/kg; SCH 3.0, SCH23390 3.0 mg/kg; HVSs, high-voltage spindles; M1, primary motor cortex; GP, globus pallidus.