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RNA mapping of Drosha deficient cells
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创建时间：
2012-03-14
相关数据集
The helicase domain of Dicer ensures essential accuracy of miRNA biogenesis in mice
Dicer ribonucleases, which generate small RNAs for the RNA interference (RNAi) and microRNA (miRNA) pathways, often have an N-terminal DExD helicase subdomain (also called HEL1). In the mammalian Dice
NIAID Data Ecosystem100
Expression data from wild-type, Dgcr8 knockout and Dicer knockout ES cells. Mus musculus
Dgcr8 and Dicer are both important components of the microRNA biogenesis pathway while Dicer is also implicated in biogenesis of other types of small RNAs such as siRNAs and mirtrons. Here we performe
NIAID Data Ecosystem40
The promoters of the key components of the miRNA processing machinery contain p53/p63-REs.
p53/p63/p73 may regulate the microRNA processing components through its responsive elements present in their promoters. * Microarray data suggest that this gene is induced in response to TA-p63/ΔN-p63
NIAID Data Ecosystem20
DGCR8 is required for microRNA maturation. Mus musculus
To determine whether DGCR8 is required for maturation of all miRNAs, we performed miRNA microarray analysis. Using RNA from wild-type ES cells as our reference sample, we observed a global loss of miR
NIAID Data Ecosystem50
Expression profile of TTHA0167-deficient Thermus thermophilus HB8 strain. Thermus thermophilus HB8
In order to find function of TTHA0167 protein from T. thermophilus HB8, we observed the expression profile of the total mRNA of the TTHA0167-deficient strain grown in a rich medium at 70°C for 480 min
NIAID Data Ecosystem20
