Crystal structure of PI3K-alpha in complex with taselisib
收藏数据链接：
官方服务：
资源简介：
Crystal structure of PI3K-alpha in complex with taselisib Descriptor: 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1H-pyrazol-1-yl)propanamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Authors: Kiefer, J.R, Eigenbrot, C, Staben, S.T, Hanan, E.J, Wallweber, H.J.A, Ultsch, M, Braun, M.G, Friedman, L.S, Purkey, H.E. Deposit date: 2022-10-25 Release date: 2022-11-30 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.989 Å) Cite: Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3K alpha. J.Med.Chem., 65, 2022
创建时间：
2022-10-25
