Significantly enriched GO terms of consensus clusters.

Cellular functions and metabolic activities are indicated by gene ontology (GO) categories that are significantly enriched in clusters ( in cumulative hypergeometric distribution tests). GO terms were taken from the SGD genome annotation file and only direct annotations were used, i.e., annotations were not propagated to their parent terms in the GO structure. Redundant terms were manually filtered and categorized into the three columns of the table. Only consensus clusters are shown and the rest of clusters are given in Table S3. The full data, all GO terms and p-values for all clusters, are provided as Dataset S2. The numbers in brackets show the number of genes in the cluster and the total number of genes with the respective annotation. Abbreviations: mito., mitochondrial; neg.reg., negative regulation; PolI and PolII, DNA-directed RNA polymerase complex I and III, respectively; RP, ribosomal protein; LSU and SSU, large and small ribosomal subunit, respectively; mito., mitochondrial; RCC, respiratory chain complex; BSP, biosynthetic process; CP, catabolic process; MP, metabolic process; ER, endoplasmatic reticulum. (*) reported is the sum of all significantly enriched amino acid biosynthetic pathways, i.e., lysine (via aminoadipic acid, 6/8), branched chain (5/7), aromatic (3/5), leucine (3/5), histidine (4/14), asparagine(glutamate-hydrolyzing, 2/2) and arginine (metabolic process, 2/2).