Additional file 4: Table S1. of Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

HP1β interacting partners in ESCs and MEFs by co-immunoprecipitation followed by LC-MS/MS analysis. Only proteins that were not identified in the corresponding control co-immunoprecipitation samples were regarded as specific. Hits found in both biological duplicates are in bold and underlined and are shown at the top. The eight proteins that were identified in both cell types are in bold and underlined and are shown at the bottom. Hits found also in negative control experiments similar to our experimental settings in the Contaminant Repository for Affinity Purification through its web interface [91] are most probably false negative interacting partners, and thus were excluded from the final list (Fig. 4a). Those few additional excluded hits are marked by an asterisk in the lists and are in gray and italics. (Control sets: CC76 CC78 CC79 CC80 CC81 CC82 with the following filters: Cell type-HEK293, Affitnity Support-Agaraose beads, Instrument Type for Mass Spectometry- LTQ-FT.) The HP1β interacting partners in MEFs were classified according to their functional annotation and biological process using Gene Ontology (GO). Only the different categories found to be statistically significant are indicated by colors and found in the legend of the pie chart on the right side of the excel sheet “HP1beta interactors MEF”. (XLSX 27.1 kb)