RFX3 is essential for the generation of functional human pancreatic islets from stem cells (1)
收藏NIAID Data Ecosystem2026-05-02 收录
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https://zenodo.org/record/13647650
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资源简介：
Wild type iPSCs (WT-iPSCs) generated and fully characterized in our laboratory were used for RFX3 knockout iPSCs (RFX3 KO iPSCs) generation. WT-iPSCs and RFX3 KO iPSCs were differentiated into pancreatic islet cells to uncover RFX3’s role during pancreatic islet development as described in the article titled “RFX3 is required for the development of human pluripotent-stem cell-derived pancreatic islets” by Memon et al. The dataset represents RNA-seq data generated from pancreatic progenitors (PPs) derived from WT-iPSCs and RFX3 KO iPSCs.
The file name: Sample name _overall sample number_read direction_001 where:
- PPs-WT-Rep1: pancreatic progenitors (PPs) derived from WT-iPSCs, replicate 1.
- PPs-WT-Rep2: pancreatic progenitors (PPs) derived from WT-iPSCs, replicate 2.
- PPs-WT-Rep3: pancreatic progenitors (PPs) derived from WT-iPSCs, replicate 3.
- PPs-KO1-Rep1: pancreatic progenitors (PPs) derived from RFX3 KO1 iPSCs, replicate 1.
- PPs-KO1-Rep2: pancreatic progenitors (PPs) derived from RFX3 KO1 iPSCs, replicate 2.
- PPs-KO1-Rep3: pancreatic progenitors (PPs) derived from RFX3 KO1 iPSCs, replicate 3.
- PPs-KO2-Rep1: pancreatic progenitors (PPs) derived from RFX3 KO2 iPSCs, replicate 1.
- PPs-KO2-Rep2: pancreatic progenitors (PPs) derived from RFX3 KO2 iPSCs, replicate 2.
- PPs-KO2-Rep3: pancreatic progenitors (PPs) derived from RFX3 KO2 iPSCs, replicate 3.
- Read direction: R1 (Forward), R2 (Reverse).
创建时间：
2025-04-12
