Differential drug resistance of CHA59, Saos-2, and HuO9 monolayer vs. sphere.
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Gray background marks higher drug sensitivity as measured by IC50 in molarity. ‘M’ represents monolayers, ‘S’ represents spheres. 17-DMAG (17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin); SU11274 ([(3Z)-N-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylene)-N-methyl-2-oxoindoline-5-sulfonamide]); RHPS4 (3,11-difluoro-6,8,13-trimethyl- 8H-quino [4,3,2-kl] acridinium methosulfate); PV1019 ([7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]).
创建时间:
2015-12-02



