Transcriptome analysis of neuroblastoma. Homo sapiens

Present material was analyzed for activation of intracellular pathways in neuroblastoma compared to normal tissues (neural crest cells, healthy adrenal gland). Overall design: Neuroblastoma samples were obtained from pediatric patients who had undergone surgery. Samples were formain fixed and embedded in paraffin. Tumors were evaluated by a pathologist to confirm the diagnosis and estimate the tumor cell numbers. All tumor samples used in this study contained at least 80% of tumor cells.