RNA-seq analysis of WT and NCOR1f/f,Cd4Cre naive CD4+ T cells
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https://www.ncbi.nlm.nih.gov/sra/SRP225856
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资源简介:
The differentiation of naïve CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-modifying enzymes in Th cells is yet unknown. Here we determined transcriptional changes in naive CD4+ T cells upon deletion of the cofactor NCOR1. Overall design: mRNA expression profiles of WT and NCOR1f/f,Cd4Cre naive CD4+ T cells were generated by deep sequencing.
创建时间:
2020-04-28



