aDuration since diagnosis of CIS or clinically definite MS until study enrollment. bIKA: Social Insurance Institute, OPAD: Insurance institute for employees of the public sector, ΟAEE: Insurance insti
*Plus-minus values are means ± SD.†The body-mass index is the weight in kilograms divided by square of the height in meters.‡Values shown are medians (interquartile ranges).eGFR: estimated glomerular
