Molecular bases for tumor induced exhaustion in CD8 T cells
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Molecular bases for tumor induced exhaustion in CD8 T cells
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创建时间：
2013-12-31
相关数据集
Association between HPK1 expression and T-cell exhaustion. Association between HPK1 expression and T-cell exhaustion
We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.
NIAID Data Ecosystem60
Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice
CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie
NIAID Data Ecosystem60
HSF1 excludes CD8+ T cells from breast tumors via suppression of CCL5 [4T1 tumors]. HSF1 excludes CD8+ T cells from breast tumors via suppression of CCL5 [4T1 tumors]
Breast cancer cells or tumors underwent RNA-sequencing or single cell RNA-sequencing to study the role of HSF1 in tumor-immune interactions. Overall design: Human MDA-MB-231 and mouse 4T1 cells expres
NIAID Data Ecosystem30
Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.
Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.
NIAID Data Ecosystem60
IL-12 induces myeloid cells in situ to cross-present antigen
Myeloid-derived cells comprising the tumor stroma represent a heterogeneous population of cells critical to the structure, function and growth of established cancers. We have recently found that engin
NIAID Data Ecosystem30
