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Identification of Novel Mutations in SARS-CoV-2 ORF8 Gene: Insights into Potential Functional Implications

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DataCite Commons2025-06-01 更新2025-05-07 收录
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https://figshare.com/articles/dataset/Identification_of_Novel_Mutations_in_SARS-CoV-2_ORF8_Gene_Insights_into_Potential_Functional_Implications/28829459/1
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This dataset contains supplementary materials related to the identification and analysis of novel mutations in the ORF8 gene of SARS-CoV-2. The files include:<b>Consensus Sequence (FASTA Format) </b>: The complete genome sequence analyzed in this study, highlighting key mutations.<b>Variant Call File (VCF) </b>: Detailed variant calls generated from genomic alignment and annotation pipelines.<b>Mutation List </b>: A curated list of identified mutations, including their genomic positions, amino acid changes, and predicted functional impacts.<b>Scripts and Code </b>: Custom scripts used for bioinformatics analysis (e.g., mutation calling, annotation, and visualization).These data support the findings reported in the manuscript titled <i>"Identification of Novel Mutations in SARS-CoV-2 ORF8 Gene: Insights into Potential Functional Implications" </i>. The mutations identified, such as <b>ORF8:p.R52I </b>and <b>Q27stop </b>, are potentially novel and may provide insights into viral evolution, immune evasion, and pathogenicity. Researchers are encouraged to reuse and build upon these data to further investigate the biological significance of these mutations.
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figshare
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2025-04-20
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