Transcriptional profiling analysis of the effects of Ssn3 inhibition in Candida albicans

Genome-wide transcriptional profiles of Candida albicans without and with inhibition of an analog sensitive Ssn3 using 3-MB-PP1. Overall design: Using Candida albicans with an analog sensitive version of Ssn3, we performed proteomics and transcriptomics analyses of effects of Ssn3 inhibition in medium that does not normally stimulate hyphal growth. Cultures were grown in triplicate and analyzed immediately after inhibition and at 3h after inhibition.