Immunomodulatory Microneedle Patch for Cardiac Repair in Rodent and Porcine Models of Myocardial Infarction

NIAID Data Ecosystem2026-05-10 收录

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https://www.ncbi.nlm.nih.gov/sra/SRP484480 数据链接链接失效反馈

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Our goal is to underscore the therapeutic promise of IL-4 treatment in modulating post-MI immune dynamics and fostering cardiac tissue repair in acute MI.

创建时间：

2025-09-30

Intrapericardial administration of secretomes from endometrial-derived mesenchymal stromal cells: effects on immune-related genes in a porcine model of myocardial infarction. Intrapericardial administration of secretomes from endometrial-derived mesenchymal stromal cells: effects on immune-related genes in a porcine model of myocardial infarction

心肌梗死免疫治疗

间充质基质细胞

Using a porcine model of acute myocardial infarction, we explored the potential effect of secretomes from endometrial-derived mesenchymal stromal cells (endMSCs) and from IFNγ/TNFα-primed endMSCs on i

NIAID Data Ecosystem40

Bone marrow naÃ¯ve B lymphocytes improve heart function after myocardial infarction [scRNA-Seq]

心肌梗死免疫治疗

单细胞RNA测序

We provided a single cell mRNA-seq analyses of mouse bone marrow revealing B cell development arrest in the bone marrow after MI, which was restored by treatment of empagliflozin (EMPA). Overall desig

NIAID Data Ecosystem20

Data Sheet 1_Interleukin-10 exhibit dose-dependent effects on macrophage phenotypes and cardiac remodeling after myocardial infarction.pdf

心肌梗死免疫治疗

细胞因子剂量效应

IntroductionInterleukin-10 (IL-10) is a potent immunomodulatory cytokine widely explored as a therapeutic agent for diseases, including myocardial infarction (MI). High-dose IL-10 treatment may not ac

NIAID Data Ecosystem10

Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction

心肌梗死免疫治疗

CD28信号通路调控

Both conventional and regulatory CD4+ T-cells rely on costimulatory signals mediated by cell surface receptors including CD28 for full activation. We showed previously that stimulation of CD4+ Foxp3+

NIAID Data Ecosystem20

Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction

心肌梗死免疫治疗

CD28抗体实验研究

Both conventional and regulatory CD4+ T-cells rely on costimulatory signals mediated by cell surface receptors including CD28 for full activation. We showed previously that stimulation of CD4+ Foxp3+

Figshare2020-04-16 更新20

Immunomodulatory Microneedle Patch for Cardiac Repair in Rodent and Porcine Models of Myocardial Infarction

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