RNA-seq of MUTZ3 cells in experiments to investigate EVI1 regulation
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https://www.ncbi.nlm.nih.gov/sra/ERP126039
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We investigated whether GATA2 enhancer-driven transcription of EVI1 in inv(3)/t(3;3) is reversible in leukemia cells. In primary inv(3)/t(3;3) AML, immature CD34+CD15- cells can be discriminated from more mature CD34-CD15- and CD34-CD15+ cells. Besides, we also investigated the effect of deleting a MYB binding site on these cells using CRISPR/Cas9.
创建时间:
2023-10-13



