HERV1-env dependent unfolded protein response activation is a potential initiator of T cell autoreactivity in autoimmune liver disease.
收藏NIAID Data Ecosystem2026-04-30 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP217508
下载链接
链接失效反馈官方服务：
资源简介：
Here we report Human Endogenous Retrovirus 1 (HERV1-env) induction of endoplasmic reticulum (ER) stress with Unfolded Protein Response (UPR) activation, through its interaction with ATF6.ATF6a up-regulates RORC, STAT3 and TBX21 and induces IL-17A and INF-? production in Tregs by binding to promoter sequences. Overall design: ChIP-DNA from FACS-sorted memory Tregs from 5 subject groups
创建时间：
2022-08-05
