Effects of monotherapy with peramivir or favipiravir on oseltamivir-resistant K/2785 virus infection in mice.

aIntramuscular (peramivir) or oral (favipiravir) treatments were administered twice a day for five days starting from 4 hpi.
bMDD, mean day of death for mice that died prior to 14 dpi. Fisher’s exact test was applied to determine the statistical significance of differences in the survival rates (*, P<0.05, **, P<0.01, and ***, P<0.001 compared with the placebo mice group).