Gene expression profiling in B220+ from normal spleen, VavPBcl2/vector and VavPBcl2/Myc lymphomas

Follicular lymphoma (FL) is the second most common forms of B cell lymphoma that result from the expansion of germinal center (GC) B cells. Here, we aimed to find differential expression of genes between noemal spleen, indoent FL (VavPBcl2/vector) and transformed and aggressive FL (VavPBcl2/MYC) in our mouse model. Using RNAseq we profiled murine purified B220+ cells from normal spleen (n=4), lymphomas transduced with empty vector (n=8) or Myc (n=8)