The PFAS-Tox Database
收藏资源简介:
The PFAS-Tox Database is a useful tool for searching, filtering, and identifying peer reviewed research on the health and toxicological effects of the included PFAS. In this summary of the evidence map we provide examples of data gaps and clusters revealed by the database, with the goal of helping direct future research efforts, facilitate systematic reviews (e.g. on immune effects, mixtures of PFAS, or effects of short chain PFAS), inform regulatory risk assessments, and improve opportunities for cross-disciplinary coordination. We also discuss how this tool supports scientists, regulatory agencies, and other individuals by increasing awareness and access to current evidence regarding the health effects associated with PFAS exposure.
PFAS-Tox数据库是一款用于检索、筛选及鉴定同行评议研究的实用工具,相关研究聚焦于数据库收录的全氟和多氟烷基物质(Per- and Polyfluoroalkyl Substances, PFAS)的健康效应与毒理学影响。在本证据图谱综述中,我们展示了该数据库揭示的数据缺口与研究集群案例,旨在为未来研究方向提供指引,助力系统综述(例如针对免疫效应、PFAS混合物或短链PFAS效应的综述)的开展,为监管风险评估提供参考,并为跨学科协作创造更多契机。此外,我们还探讨了该工具如何通过提升对PFAS暴露相关健康效应的现有证据的认知与获取途径,为科研人员、监管机构及其他相关人员提供支持。




