One-Pot Synthesis of 7,9-Dialkylpurin-8-one Analogues: Broad Substrate Scope

The one-pot and direct synthesis of 7,9-dialkyl­purin-8-one analogues with broad substrate scope has been developed. This copper-catalyzed C–H oxidation reaction could avoid multistep synthesis of quaternary ammonium salts and expand the scope of halogenated alkanes. Moreover, benzimida­zole derivatives are also applicable in the catalytic system.