Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor
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Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor Descriptor: Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-[3-[(dimethylamino)methyl]-5-methyl-phenyl]-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide Authors: Ogg, D.J, Howard, T, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. Deposit date: 2020-01-21 Release date: 2020-05-27 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3.38 Å) Cite: Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors. J.Am.Chem.Soc., 142, 2020
创建时间：
2020-01-21
