Physiological and Transcriptomic Changes in the Hypothalamic-Neurohypophysial System after 24 H of Furosemide-Induced Sodium Depletion

Conclusions: We thus have identified novel genes that might regulate vasopressin gene expression in the hypothalamus controlling the magnocellular neurons secretory response to body sodium depletion and consequently hypotonic stress.结论：本研究现已鉴定出若干新型基因，此类基因或可调控下丘脑中加压素基因（vasopressin gene）的表达，进而影响下丘脑大细胞神经元对机体钠耗竭及后续低渗应激的分泌反应。