Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the inhibitor GC-67
收藏Protein Data Bank Japan2024-01-31 更新2026-04-25 收录
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Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the inhibitor GC-67 Descriptor: (2~{S})-1-(3,4-dichlorophenyl)-4-(4-methoxypyridin-3-yl)carbonyl-~{N}-(thiophen-2-ylmethyl)piperazine-2-carboxamide, 3C-like proteinase nsp5 Authors: Strater, N, Muller, C.E, Sylvester, K, Weisse, R.H, Useini, A, Gao, S, Song, L, Liu, Z, Zhan, P. Deposit date: 2023-08-15 Release date: 2023-12-06 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.322 Å) Cite: Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability. J.Med.Chem., 66, 2023
创建时间：
2023-08-15
