Mean specific activity measurements and activation quotients for BDD-FVIII muteins in cell supernatants.
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IU = International FVIII Units. Activity was normalized to the FVIII expression level measured by ELISA. *Mean values for activity and activation quotient. Activity assays were carried out using 2–3 of the highest-expressing lines chosen from 22–45 clones per mutein that were evaluated for FVIII expression levels. †Standard deviation (SD) of the mean specific activity or activation quotient. ‡Ratio of two-stage coagulation activity divided by one-stage coagulation activity. Mean specific activity measurements and activation quotients for BDD-FVIII muteins in cell supernatants.
创建时间：
2015-01-23
