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Next Generation Sequencing (NGS) for the identification of markers disregulated in B-ALL cells following activation with the agonist CD40 antibody.

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE202862
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The goal of this study was to identify through NGS transcriptomic (RNAseq), transcripts up and down-regulated, following the i.v. treatment of B-ALL Patient-Derived Xenotransplanted (PDX) mice (two models; #1 and #2) with anti-CD40 agonist antibody. Total mRNA were extracted from hCD45+ B-ALL cells purified from the BM of PDX-mice.
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2024-11-18
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