Mthfd1

ENCODES a protein that exhibits formate-tetrahydrofolate ligase activity (ortholog); methenyltetrahydrofolate cyclohydrolase activity (ortholog); methylenetetrahydrofolate dehydrogenase (NAD+) activity (ortholog); INVOLVED IN 10-formyltetrahydrofolate biosynthetic process (ortholog); heart development (ortholog); methionine biosynthetic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; altered folate mediated one-carbon metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); cleft lip (ortholog); cleft palate (ortholog); FOUND IN cytosol (ortholog)

编码一种展现出甲酸-四氢叶酸连接酶活性（同源）；甲烯基四氢叶酸环化水合酶活性（同源）；甲基四氢叶酸脱氢酶（NAD+）活性（同源）；参与10-甲酰四氢叶酸生物合成过程（同源）；心脏发育（同源）；蛋氨酸生物合成过程（同源）；参与改变的四氢叶酸代谢途径；改变的四氢叶酸介导的一碳代谢途径；四氢叶酸代谢途径；与腹主动脉瘤（同源）相关；唇裂（同源）；腭裂（同源）；存在于细胞质中（同源）