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Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor

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Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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Human cyclin dependent kinase 2 complexed with the CDK4 inhibitor Descriptor: (13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25 ),18,20-HEPTAENE-23,26-DIONE, Cell division protein kinase 2 Authors: Ikuta, M. Deposit date: 2006-06-17 Release date: 2007-06-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure Bioorg.Med.Chem.Lett., 16, 2006
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2006-06-17
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