Source Data and MAGs for FMT-HIV Butyrate Analysis

This dataset contains 279 non-redundant metagenome-assembled genomes (MAGs),quant_bins-derived MAG abundance proxies, functional annotation tables, anddownstream statistical result tables derived from a longitudinal cohort of HIV-infected patients undergoing fecal microbiota transplantation (FMT). Files include:- all_279_MAGs_unique_contigs.fasta: unified 279-MAG reference used for competitive read quantification (SHA-256: 6193b7eabeb0cbd5c757aaff346da54da74b06975411b0800eefa920a403721c).- scripts_v3.tar.gz: analysis pipeline scripts (run_all.R, build_matrix.py, but_classification_pipeline.sh, but_classification.R) (SHA-256: 213ed9486a82fd56f93b2d5db41db7e06829844dbb0efed3a069f7a6f2fc6687).- supplementary_v3.tar.gz: downstream statistical result tables (LMM, Top15, paired bootstrap, Nadir CD4, turnover) (SHA-256: 29a5052acbaef287086ba4a7af7ace861c11a58d3ad3f7b08a1e0cf57f2dd1e3).- but_candidate_assignment.csv: per-candidate But classification result (SHA-256: 53a70f395fad7a3eed7bb5701d58acb57bc7d80df5d6c207bb414b78fbf0f423).- run_all.R, build_matrix.py: standalone copies for review. The But-supported classification is based on sequence/phylogeny-supportedcandidate butyryl-CoA:acetate CoA-transferase proteins, not on experimentalvalidation. Note: v3 supersedes v2 and v1. The v1 abundance matrix used a single P01assembly as the Salmon reference, which was not representative of all 279MAGs. All analyses reported in the associated manuscript use the v3 filesand the But-supported classification in this record.