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Genome-wide chromatin and gene expression profiling during memory formation and maintenance in adult mice. [Data Record 5: Predicted CRM regions]

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Figshare2016-07-20 更新2026-04-29 收录
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DESCRIPTIONNeuronal and non-neuronal cis-regulatory modules in tissues ACC and CA1 were predicted, together with their activity, using a discriminative random forest classifier RFECS that was trained on a published set of positive and negative transcription factor binding sites and histone post-translational modifications.DATA REPOSITORIESEPIGENOME BROWSER (https://memory-epigenome-browser.dzne.de/)Contains the visualisation tracks for the CRMs (i.e. positions of CRMs) under category "ENHANCER-DATA". Sample names include cell-type (NonNeuron or Neuron) and tissue (ACC or CA1) separated by dashes. GFF files can also be downloaded for local visualisation.FigshareThe tables here contain all predicted cis-regulatory modules for each cell-type and tissue combination, where each table includes the CRM coordinates and the RFECS probabilities for each CRM.DATA GENERATIONThe binary file containing the RFECS trained forest used for the CRM predictions can be found in Figshare (https://dx.doi.org/10.6084/m9.figshare.3153406), and a clarification on how to run the analysis can be found in the reference mentioned below.
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2016-07-20
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