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Transcriptional changes and microRNA expression profiles during NeuroD1-mediated astrocyte-to-neuron conversion

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214749
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To reveal the molecular mechanisms underlying astrocyte-to-neuron reprogramming, we performed RNA-seq analysis on human astrocyte cultures (HA1800) during NeuroD1(ND1)-mediated neuronal reprogramming. Transcriptomic and microRNA (miRNA) expression profiles of control (GFP) and ND1-transduced astrocytes at 2 and 6 days post infection were compared by RNA-seq.
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2023-07-11
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