Our study revealed that hypoxia inducible factor 2 alpha, Hif2 alpha, is a downstream target of estrogen signaling in mouse uterine stroma at the time of implantation. Further, conditional deletion of
Implantation of the early embryo—the blastocyst—in the uterine wall to establish a pregnancy is remarkably inefficient in humans for reasons that remain largely unexplained1–3. In recent years, the vo
