Expression data from thioglycollate-elicited peritoneal macrophages from 129S6/SvEvTac and C57BL/6 mice. Mus musculus

Strain differences influence susceptibility to atherosclerosis. Apolipoprotein E-null mice on a C57BL/6 genetic background (B6-apoE) are highly susceptible to atherosclerosis in the aortic root area compared with those on a 129S6/SvEvTac background (129-apoE). To explore strain-specific differences affecting the susceptibility to atherosclerosis, we performed microarray analysis of macrophages from wild type mice of each strains. Overall design: Peritoneal macrophages were harvested from 3-month-old male and female 129S6/SvEvTac and C57BL/6 mice after the intraperitoneal injection of thioglycollate medium.