Immunodominant CSP and AMA1 peptide pools by ELISpot assay.

The peptide pools that were most strongly recognized at each time point by a volunteer demonstrating an overall positive response were arbitrarily identified as immunodominant if the response to that pool exceeded one-third the value of the responses to the pool with the peak response in that volunteer. The number of volunteers who met criteria for immunodominance for a given peptide pool is shown in each box. Responses to CSP pools were consistent in both Groups but more variable to AMA1 in Group 1 and Group 2.