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Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan784

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4agl
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资源简介:
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan784 Descriptor: 2,4-BIS(IODANYL)-6-[[METHYL-(1-METHYLPIPERIDIN-4-YL)AMINO]METHYL]PHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION Authors: Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. Deposit date: 2012-01-30 Release date: 2012-03-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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2012-01-30
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