MENOPAUSAL PHENOTYPES AND CARDIOMETABOLIC RISK: TOWARD AN INTEGRATED APPROACH TO EARLY IDENTIFICATION AND PERSONALIZED PREVENTION

Background. Menopause is a heterogeneous biological transition rather than a uniform clinical state. Women of the same chronological age and menopausal stage may differ in vasomotor symptoms, body-fat distribution, lipid and glucose metabolism, vascular function, sleep, and inflammatory status. These differences may contribute to distinct cardiometabolic risk profiles.