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Crystal structure of wild type Plasmodium falciparum DHFR-TS complexed with BT3, NADPH, and dUMP

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of wild type Plasmodium falciparum DHFR-TS complexed with BT3, NADPH, and dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5,5'-[propane-1,3-diylbis(oxy-4,1-phenylene)]bis(6-ethylpyrimidine-2,4-diamine), Bifunctional dihydrofolate reductase-thymidylate synthase, ... Authors: Chitnumsub, P, Jaruwat, A, Tarnchampoo, B, Yuthavong, Y. Deposit date: 2018-06-12 Release date: 2019-04-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance. ACS Med Chem Lett, 9, 2018
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2018-06-12
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