we performed a genome-wide synthetic lethal screen, using CRISPR-Cas9 genome editing, to identify potential therapeutic targets specific for ATRX-mutated cancers. In isogenic hepatocellular carcinoma

NIAID Data Ecosystem10

Synthetic lethality with PI3K inhibition in EBV associated Gastric Cancer

合成致死筛选

PI3K靶向治疗

Gastric cancer is the third leading cause of cancer death, responsible for over 1 million new cases per year. The Cancer Genome Atlas (TCGA) identified that EBV infects nearly 10% of all gastric carci

NIAID Data Ecosystem30

Gene expression data of nasopharyngeal carcinoma (NPC) cell and Podoplanin (PDPN) siRNA treatment

鼻咽癌基因表达

癌症靶点预测

Podoplanin, a transmembrane sialomucin-like glycoprotein, is now widely used as a marker for lymphatic endothelial cells and fibroblastic reticular cells in lymphoid organs, but its study in nasophary

NIAID Data Ecosystem10

CoCaNet2

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