Glycolytic shift during West Nile virus infection provides new therapeutic opportunities [Cerebellum]

To investigate the in vivo metabolic changes during WNV infection in a mouse model, we infected mice with WNV NY99 to compare to uninfected (mock) mice. We also use two compounds targeting energetic metabolism to analysed their effects on WNV infection We then performed gene expression profiling analysis using data obtained from RNA-seq from infected vs uninfected mice and treated mice. Overall design: Comparative gene expression profiling analysis of brain RNA-seq data for mice infected with WNV vs uninfected mice