Absolute value of correlation coefficients between empirically derived and experimentally derived hydrophobicity scales.

The largest significant correlation in each row is highlighted in bold.aMean RSA of residues in protein structures, as calculated by Rose et al.[2].bMean RSA of residues in protein structures, as given in column 2 of Table S3 in File S1.cMean RSA of residues in protein structures, as given in column 3 of Table S3 in File S1.dFraction of 100% buried residues, as given in column 4 of Table S3 in File S1.eFraction of 95% buried residues, as given in column 5 of Table S3 in File S1.fTransfer energy from vapor to water [26].gHybrid scale based on transfer energy from vapor to water and on the percentages of 95% and 100% buried residues in protein structures [27].hTransfer energy from cyclohexane to water [29].i between the folded and unfolded state of a mutated membrane-inserted protein, outer membrane phospholipase A [31].kTransfer energy calculated from molecular-dynamic simulations of side-chain analogs within a bilayer [30].lTransfer energy between octanol and water [28].mTransfer energy of pentapeptides between octanol and water [32].Correlation not statistically significant; all other correlations are significant at .