Tofu decreases serum lipid levels and modulates hepatic gene expression involved in lipid metabolism in rats

The GeneChip data was normalized and summarized by using SuperNORM data service (Skylight Biotech Inc.). Significance of expressional change among groups was tested by 2-way ANOVA on the normalized CEL data, which was deposited in a tab-separated ASCII text format. Principal components were identified on the summarized gene data.本研究采用斯凯莱特生物科技公司（Skylight Biotech Inc.）提供的SuperNORM数据分析服务（SuperNORM data service），对基因芯片（GeneChip）数据完成标准化与汇总处理。针对以制表符分隔的ASCII文本格式存储的标准化CEL数据，采用双向方差分析（2-way ANOVA）检验各组间基因表达变化的显著性；随后基于汇总后的基因表达数据，识别得到主成分（Principal components）。